TY - CHAP M1 - Book, Section TI - Chapter 73. Hematopoietic Stem Cell Transplantation and Graft-versus-Host Disease A1 - Crawford, Stephen W. A1 - Folz, Rodney J. A1 - Sullivan, Keith M. A2 - Hall, Jesse B. A2 - Schmidt, Gregory A. A2 - Wood, Lawrence D.H. PY - 2005 T2 - Principles of Critical Care, 3e AB - The principles of and approaches to the critical care of hematopoietic stem cell transplant recipients are similar to those for other immunosuppressed hosts.Specific complications tend to occur within well-defined time periods and are influenced by the type of stem cell transplant.The primary distinguishing features of hematopoietic stem cell transplant recipients are the high prevalence of graft rejection, graft-versus-host reactions, and chemoradiotherapy-related toxicities.Acute graft-versus-host disease represents a major problem to allogeneic hematopoietic stem cell transplantation.Hepatic veno-occlusive disease is the most common lethal chemoradiotherapy-related toxicity after hematopoietic stem cell transplantation.When prophylactic treatment is used, diffuse pneumonia due to cytomegalovirus is uncommon after hematopoietic stem cell transplantation.Idiopathic pneumonia syndrome remains a major cause of mortality, and no treatment has been proved effective. SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2023/03/25 UR - accesssurgery.mhmedical.com/content.aspx?aid=2294199 ER -