TY - CHAP M1 - Book, Section TI - Takotsubo Syndrome A1 - Zerbib, Yoann A1 - Brault, Clément A1 - Slama, Michel A2 - Schmidt, Gregory A. A2 - Kress, John P. A2 - Douglas, Ivor S. PY - 2023 T2 - Hall, Schmidt and Wood’s Principles of Critical Care, 5th Edition AB - KEY POINTSCatecholamine toxicity seems to be the key mechanism of takotsubo.Emotional or physical triggers are almost always present in the history of takotsubo.The dominant pattern is the apical ballooning form.Takotsubo is a diagnosis of exclusion: myocardial infarction and myocarditis should be ruled out, generally requiring coronary angiography. MRI may also be useful.Echocardiography is the main tool to diagnose, follow, and detect complications.Severe cardiac failure and cardiogenic shock are the main causes of ICU hospitalization.Left ventricular outflow tract obstruction is frequent in patients with takotsubo.Management is based in very little evidence: anticoagulants, beta-blockers (in case of obstruction), levosimendan, and mechanical hemodynamical support have been advocated. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/10/12 UR - accesssurgery.mhmedical.com/content.aspx?aid=1201882095 ER -