TY - CHAP M1 - Book, Section TI - Judging the Adequacy of Fluid Resuscitation A1 - Schmidt, Gregory A. A2 - Schmidt, Gregory A. A2 - Kress, John P. A2 - Douglas, Ivor S. PY - 2023 T2 - Hall, Schmidt and Wood’s Principles of Critical Care, 5th Edition AB - KEY POINTSOf critically ill patients with conventional indications for a fluid bolus, only about half will respond with a meaningful increase in perfusion.Fluid therapy that does not boost perfusion may cause harm by impairing lung function, producing edema in other organs, or contributing to endothelial dysfunction.Static hemodynamic parameters, such as central venous pressure or pulmonary artery occlusion pressure, have little value in guiding fluid therapy.Fluid responsiveness can be predicted using cardiopulmonary interactions to probe circulatory function or through passive leg raising.Dynamic fluid-responsiveness predictors are accurate but require careful attention to preconditions for validity. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/10/14 UR - accesssurgery.mhmedical.com/content.aspx?aid=1201800942 ER -