TY - CHAP M1 - Book, Section TI - HLA and ABO Desensitization A1 - Cagliani, Joaquin A A1 - Kolwitz, Christine E A1 - Montgomery, Robert A A2 - Molmenti, Ernesto Pompeo PY - 2023 T2 - Molmenti’s Kidney and Pancreas Transplantation: Operative Techniques and Medical Management, 2e AB - Highly polymorphic antigens expressed on the surface of cellsHave crucial roles in defense against foreign pathogens and in tumor immune surveillanceAntibodies against these antigens can develop as a result of pregnancy, transplantation, or blood transfusionHuman leukocyte antigen (HLA) sensitization adversely affects both access to and the outcomes of transplantationImproved identification of HLA molecules and of the specificity of HLA antibodies has improved transplant graft survivalDesensitization of anti-HLA antibodies is essential to enable meaningful progress in the field of transplantation and increase the likelihood that a patient will receive a transplant offer. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/10/10 UR - accesssurgery.mhmedical.com/content.aspx?aid=1194180058 ER -