TY - CHAP M1 - Book, Section TI - Parathyroidectomy A1 - Ellison, E. Christopher A1 - Zollinger, Jr., Robert M. A1 - Pawlik, Timothy M. A1 - Vaccaro, Patrick S. A1 - Bitans, Marita A1 - Baker, Anthony S. PY - 2022 T2 - Zollinger’s Atlas of Surgical Operations, 11e AB - Hyperparathyroidism is a common endocrine disorder usually cured when treated surgically. Parathyroid gland overactivity documented by appropriate laboratory studies may be associated with general hyperplasia of the parathyroid glands or with an adenoma involving one or more parathyroid glands. Kidney stones, osteopenia/osteoporosis, gastrinoma, recurrent pancreatitis, and other conditions are some of the clinical disorders that imply a disorder of the parathyroid glands. Hypercalcemia is discovered as a result of more frequent calcium determinations performed as part of a general screening survey. Hyperparathyroidism is associated with gastrinoma in approximately one-third of patients with the familial multiple endocrine neoplasia type I (MEN I) syndrome. A mitogenic cause for the relatively high incidence of recurrent hyperparathyroidism in the familial MEN I syndrome suggests the need for a radical approach, which may consist of total parathyroidectomy with parathyroid autotransplantation into the muscle in the nondominant forearm versus removal of three and a half parathyroid glands. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/10/13 UR - accesssurgery.mhmedical.com/content.aspx?aid=1187823353 ER -