TY  - CHAP
M1  - Book, Section
TI  - Drug-Induced Liver Injury
A1  - Trilianos, Panagiotis
A1  - Pyrsopoulos, Nikolaos T.
A2  - Molmenti, Ernesto Pompeo
A2  - Santibañes, Martin de
A2  - Santibañes, Eduardo de
PY  - 2021
T2  - Liver Transplantation: Operative Techniques and Medical Management
AB  - Drug-induced  liver  injury  (DILI)  is  a  term  used  to  describe  the  hepatotoxic  adverse  effect  of  prescribed  and  over-the-counter  medications,  as  well  as  botanicals  and  herbal  and  dietary  supplements  (HDS).It  may  be  further  divided  into:Intrinsic:  dose-dependent  hepatotoxicity,  expected  in  all  individuals  where  dose  threshold  is  exceededIdiosyncratic:  mostly  dose-independent  hepatotoxicity,  rarely  occurring  in  susceptible  individualsThe  sequelae  of  DILI  can  encompass  the  entire  spectrum  of  liver  disease,  ranging  from  asymptomatic,  self-limited  acute  hepatitis  to  fulminant  liver  failure  and  from  chronic  hepatitis  to  advanced  fibrosis  and  cirrhosis.  
SN  - 
PB  - McGraw Hill
CY  - New York, NY
Y2  - 2024/04/19
UR  - accesssurgery.mhmedical.com/content.aspx?aid=1180107255
ER  -