TY - CHAP M1 - Book, Section TI - Neoadjuvant and Adjuvant Radiotherapy for Non–Small-Cell Lung Cancer A1 - Mak, Raymond H. A1 - Baldini, Elizabeth H. A2 - Sugarbaker, David J. A2 - Bueno, Raphael A2 - Burt, Bryan M. A2 - Groth, Shawn S. A2 - Loor, Gabriel A2 - Wolf, Andrea S. A2 - Williams, Marcia A2 - Adams, Ann PY - 2020 T2 - Sugarbaker’s Adult Chest Surgery, 3e AB - Radiation therapy (RT) plays an important role in the management of locally advanced non–small-cell lung cancer (NSCLC). In the neoadjuvant (preoperative) setting, thoracic RT with concurrent chemotherapy (CT) can be an effective means for downstaging mediastinal disease and improving the likelihood of complete resection. In the adjuvant (postoperative) setting, RT may decrease the risk of locoregional recurrence for patients with high-risk disease such as pathologic N2 involvement and/or positive margins. Modern techniques of radiation treatment planning and delivery have improved the safety profile and efficacy of thoracic RT. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/11/11 UR - accesssurgery.mhmedical.com/content.aspx?aid=1170411485 ER -