TY - CHAP M1 - Book, Section TI - Congenital Hearing Loss A1 - Chan, Yvonne A1 - Goddard, John C. PY - 2019 T2 - K.J. Lee’s Essential Otolaryngology: Head and Neck Surgery, 12e AB - Deafness is the most common sensory defect (1 in 1000-2000 births; there are roughly 4 million births in the United States per year).Early identification allows appropriate intervention as soon as indicated.Fifty percent of congenital hearing loss is due to nongenetic factors.Environmental (25% of all congenital hearing loss cases)Infections (TORCH)OtotoxicityPrematurityExtracorporeal membrane oxygenation (ECMO)HypoxiaIdiopathic (25% of all congenital hearing loss cases)Fifty percent of congenital hearing loss is due to genetic factorsSeventy percent of genetic cases are nonsyndromicSeventy-five percent to 80% of nonsyndromic deafness is inherited through autosomal recessive (AR) patterns.Eighteen percent to 20% of nonsyndromic deafness is inherited through autosomal dominant (AD) patterns.One percent to 3% of nonsyndromic deafness is classified as X-linked, or chromosomal disorders.Thirty percent of genetic cases are syndromicThe majority of these cases are passed on through AR or X-linked inheritance. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesssurgery.mhmedical.com/content.aspx?aid=1172369427 ER -