TY  - CHAP
M1  - Book, Section
TI  - Management of Shock
A1  - Thompson, Callie M.
A1  - Maier, Ronald V.
A2  - Moore, Ernest E.
A2  - Feliciano, David V.
A2  - Mattox, Kenneth L.
PY  - 2017
T2  - Trauma, 8e
AB  - Shock  is  defined  as  the  inadequate  delivery  of  oxygen  to  tissues  leading  to  cellular  dysfunction  and  injury.  In  1872  Gross  described  shock  as  a  “rude  unhinging  of  the  machinery  of  life.”1  Although  this  definition  is  less  than  precise,  to  this  day  it  illustrates  the  physiologic  derangements  of  decompensated  shock.  Significant  hypoperfusion  and  cellular  injury  may  occur  despite  normal  systemic  blood  pressure,  so  equating  shock  with  hypotension  and  cardiovascular  collapse  is  a  vast  oversimplification  and  results  in  delayed  recognition  of  early  shock,  when  intervention  is  most  effective  at  preventing  end-organ  dysfunction.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accesssurgery.mhmedical.com/content.aspx?aid=1147414727
ER  -