TY - CHAP M1 - Book, Section TI - Natural History and Principles of Management of Pancreatic Neuroendocrine Tumors A1 - Lebastchi, Amir H. A1 - Callender, Glenda G. A2 - Morita, Shane Y. A2 - Balch, Charles M. A2 - Klimberg, V. Suzanne A2 - Pawlik, Timothy M. A2 - Posner, Mitchell C. A2 - Tanabe, Kenneth K. PY - 2018 T2 - Textbook of Complex General Surgical Oncology AB - Pancreatic neuroendocrine tumors (PNETs) are tumors that originate from the islet cells of the pancreas and are also often referred to as islet cell tumors. With an estimated incidence of about 2.5 to 5 per 100,000 persons per year, these uncommon tumors represent only 1% to 2% of pancreatic malignancies.1 In contrast to pancreatic adenocarcinoma, the incidence of PNETs appears to have increased over the past decades.2,3 Autopsy studies have shown that small, asymptomatic PNETs may occur in as many as 10% of people.4,5 Thus, increased detection, particularly because of increased imaging and advances in imaging technology, may account for much of the rise in the incidence of PNETs.6-8 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesssurgery.mhmedical.com/content.aspx?aid=1145765162 ER -