TY - CHAP M1 - Book, Section TI - Colorectal Cancer: Molecular Biology and Inherited Cancer Syndromes A1 - Dineen, Sean A1 - Rodriguez-Bigas, Miguel A. A2 - Morita, Shane Y. A2 - Balch, Charles M. A2 - Klimberg, V. Suzanne A2 - Pawlik, Timothy M. A2 - Posner, Mitchell C. A2 - Tanabe, Kenneth K. PY - 2018 T2 - Textbook of Complex General Surgical Oncology AB - The treatment of colorectal cancer (CRC) is evolving continuously and many important advances have recently led to improved prognosis. Surgery remains an integral component of multidisciplinary treatment. Targeted therapies are being developed in the laboratory and implemented clinically, thus taking advantage of major advances in understanding the molecular biology of CRC. This chapter briefly reviews the epidemiology of CRC and then the molecular biology of CRC and discusses inherited CRC syndromes, and also CRC screening and surveillance. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesssurgery.mhmedical.com/content.aspx?aid=1145762134 ER -