TY - CHAP M1 - Book, Section TI - Deep Hypothermic Circulatory Arrest A1 - Leshnower, Bradley G. A1 - Chen, Edward P. A2 - Cohn, Lawrence H. A2 - Adams, David H. PY - 2017 T2 - Cardiac Surgery in the Adult, 5e AB - Surgical therapy for aortic arch disease involves partial or complete replacement of the arch with great vessel reimplantation during a period of time when native cerebral blood flow is temporarily interrupted. In its original description, this interval of suspended cerebral perfusion required the cessation of blood flow to the entire body and was labeled hypothermic circulatory arrest (HCA). HCA employs the use of systemic hypothermia to protect the brain and visceral organs during the ischemic period, and provides a bloodless operative field to facilitate arch reconstruction. Since the initial report of the use of HCA for aortic arch replacement, cerebral protection, and circulation management techniques have evolved to enable safe, reproducible arch reconstruction with excellent neurologic outcomes.1 SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/03/28 UR - accesssurgery.mhmedical.com/content.aspx?aid=1144151217 ER -