Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content + • Hematemesis or coffee ground emesis following forceful vomiting or retching• Epigastric pain +++ Epidemiology + • Responsible for about 10% of cases of acute upper GI hemorrhage• Lesion consists of a 1- to 4-cm longitudinal tear in the gastric mucosa near the esophagogastric junction, extending through the mucosa and submucosa but not usually into the muscularis mucosae• About 75% of these lesions are confined to the stomach; 20% straddle the esophagogastric junction; and 5% are entirely within the distal esophagus• 67% of patients have a hiatal hernia• In about 90% of patients, the bleeding stops spontaneously• The majority of patients are alcoholics +++ Symptoms and Signs + • The patient first vomits food and gastric contents, followed by forceful retching and then bloody vomitus• Epigastric pain• Epigastric tenderness +++ Laboratory Findings + • HGB may be unchanged because of acute blood loss• Obtain CBC, type and cross, prothrombin time (PT), partial thromboplastin time (PTT), international normalized ratio (INR) +++ Imaging Findings + • Upper GI endoscopy: Evidence of gastric and/or distal esophageal mucosal tear with bleeding + • As in any case of acute upper GI bleeding, endoscopy should be performed emergently for diagnosis and possible treatment +++ Rule Out + • Boerhaave syndrome: rupture of the distal esophagus produced by vomiting• Other causes of upper GI hemorrhage + • Admission to ICU• Laboratory tests (type and cross, CBC, PT, PTT, INR)• NG lavage• Upper GI endoscopy +++ When to Admit + • All cases of acute GI hemorrhage should be admitted + • The bleeding can sometimes be controlled by endoscopic therapy• Surgical repair by gastrotomy and oversewing the tears +++ Surgery +++ Indications + • Persistent or recurrent bleeding after endoscopic treatment +++ Medications + • H2 blockers, proton pump inhibitors to possibly decrease risk of rebleeding +++ Treatment Monitoring + • Serial Hgb to evaluate for ongoing blood loss +++ Complications + • Recurrent or ongoing bleeding after endoscopic treatment +++ Prognosis + • Postoperative recurrence is rare +++ References ++Kortas DY. Mallory-Weiss tear: predisposing factors and predictors of a complicated course. Am J Gastroenterol. 2001;96:2863. [PubMed: 11693318] Your Access profile is currently affiliated with '[InstitutionA]' and is in the process of switching affiliations to '[InstitutionB]'. Please click ‘Continue’ to continue the affiliation switch, otherwise click ‘Cancel’ to cancel signing in. Get Free Access Through Your Institution Learn how to see if your library subscribes to McGraw Hill Medical products. Subscribe: Institutional or Individual Sign In Username Error: Please enter User Name Password Error: Please enter Password Forgot Password? Forgot Username? Sign in via OpenAthens Sign in via Shibboleth