Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content + • Endoscopic or contrast radiographic evidence of diverticulum +++ Epidemiology + • Duodenal pulsion diverticula are acquired outpouchings of the mucosa and submucosa• Found in 20% of autopsies and 5-10% of upper GI series• 90% are on the medial aspect of the duodenum• Most are solitary and within 2.5 cm of the ampulla of Vater• Rare before age 40• Symptoms are uncommon, and only 1% of cases found by x-ray warrant surgery• Wind sock type of congenital intraluminal diverticulum is rare +++ Symptoms and Signs + • Most are asymptomatic• A few patients have chronic postprandial abdominal pain or dyspepsia• May present with symptoms from complications of diverticulum-Hemorrhage-Perforation-Pancreatitis-Biliary obstruction• Wind sock type of intraluminal diverticulum usually presents with vague epigastric pain and postprandial fullness-Intestinal bleeding or pancreatitis is occasionally seen +++ Laboratory Findings + • Anemia +++ Imaging Findings + • Diverticulum visualized on upper GI contrast radiographic studies or upper GI endoscopy + • Suspect duodenal diverticula in patients with upper GI bleeding, perforation or biliary obstruction in which no other source is evident +++ Rule Out + • Other causes of upper GI perforation, bleeding, acute pancreatitis, or biliary obstruction + • Signs and symptoms of duodenal diverticula or complications• The diagnosis can be made by upper GI contrast radiographic studies or upper GI endoscopy +++ When to Admit + • Upper GI bleeding• Perforation• Biliary obstruction• Pancreatitis• Severe abdominal pain + • Excision and a 2-layer closure• Endoscopic sphincterotomy or stent placement may be preferable to treat biliary obstruction +++ Surgery +++ Indications + • All complications• Severe persistent postprandial abdominal pain or dyspepsia +++ Contraindications + • Asymptomatic patients +++ Medications + • Antacids and anticholinergics +++ Complications + • Bleeding• Perforation• Acute pancreatitis• Biliary obstruction +++ Prognosis + • Good with expedient surgical treatment of complications +++ References ++Lobo DN et al. Periampullary diverticula and pancreaticobiliary disease. Br J Surg. 1999;86:588. [PubMed: 10361174] Your Access profile is currently affiliated with [InstitutionA] and is in the process of switching affiliations to [InstitutionB]. Please select how you would like to proceed. Keep the current affiliation with [InstitutionA] and continue with the Access profile sign in process Switch affiliation to [InstitutionB] and continue with the Access profile sign in process Get Free Access Through Your Institution Learn how to see if your library subscribes to McGraw Hill Medical products. Subscribe: Institutional or Individual Sign In Error: Incorrect UserName or Password Username Error: Please enter User Name Password Error: Please enter Password Sign in Forgot Password? Forgot Username? Download the Access App: iOS | Android Sign in via OpenAthens Sign in via Shibboleth You already have access! Please proceed to your institution's subscription. Create a free profile for additional features.