Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content + • Water deficit without solute deficit• Rare in surgical patients• Water deficit can be estimated from serum Na concentration• Water deficit: ((140 - serum Na) * total body water))/140 +++ Epidemiology + • Occurs in patients unable to regulate water intake• Insensible water loss from fever• Tube feedings with inadequate water content• Diabetes insipidus +++ Symptoms and Signs + • Concentrated urine• CNS depression• Lethargy• Coma• Muscle rigidity• Tremors• Spasticity• Seizures +++ Laboratory Findings + • Hypernatremia• Low urine Na despite hypernatremia + • Water deficit usually accompanied by solute (Na+) deficit + • Physical exam• Serial serum Na + • Replacement of enough water to return serum Na concentration to normal• Treat patient with D5W unless hypotension has developed in which case hypotonic saline should be used +++ Treatment Monitoring + • Serum Na +++ Prognosis + • Excellent +++ Prevention + • Adequate water intake +++ References ++Palevsky PM et al. Hypernatremia in hospitalized patients. Ann Intern Med. 1996;124:197. [PubMed: 8533994] ++Body JJ. Current and future directions in medical therapy: hypercalcemia. Cancer. 2000;88(12 Suppl):3054. Your Access profile is currently affiliated with [InstitutionA] and is in the process of switching affiliations to [InstitutionB]. Please select how you would like to proceed. Keep the current affiliation with [InstitutionA] and continue with the Access profile sign in process Switch affiliation to [InstitutionB] and continue with the Access profile sign in process Get Free Access Through Your Institution Learn how to see if your library subscribes to McGraw Hill Medical products. Subscribe: Institutional or Individual Sign In Error: Incorrect UserName or Password Username Error: Please enter User Name Password Error: Please enter Password Sign in Forgot Password? Forgot Username? Download the Access App: iOS | Android Sign in via OpenAthens Sign in via Shibboleth You already have access! Please proceed to your institution's subscription. Create a free profile for additional features.