Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content + • Acute hyperventilation lowers Paco2 without concomitant changes in plasma bicarbonate concentration• Chronic respiratory alkalosis occurs in pulmonary and liver disease +++ Epidemiology + • May be early sign of sepsis +++ Symptoms and Signs + • Paresthesias• Carpopedal spasm• Positive Chvostek sign + • Electrolyte pattern of chronic respiratory alkalosis is the same as hyperchloremic acidosis; they can only be distinguished by ABG pH measurement + • ABG measurement• Serum electrolytes + • Chronic respiratory alkalosis does not generally require treatment +++ Complications + • Treatment of chronic respiratory alkalosis may lead to metabolic acidosis and hyperchloremia +++ References ++Adrogue HJ et al. Management of life-threatening acid-base disorders. (Two parts.) N Engl J Med. 1998;338:26, 107. ++Krapf R et al: Chronic respiratory alkalosis. The effect of sustained hyperventilation on renal regulation of acid-base equilibrium. N Engl J Med 1991;324:1394. [PubMed: 1902283] Your Access profile is currently affiliated with [InstitutionA] and is in the process of switching affiliations to [InstitutionB]. Please select how you would like to proceed. Keep the current affiliation with [InstitutionA] and continue with the Access profile sign in process Switch affiliation to [InstitutionB] and continue with the Access profile sign in process Get Free Access Through Your Institution Learn how to see if your library subscribes to McGraw Hill Medical products. Subscribe: Institutional or Individual Sign In Error: Incorrect UserName or Password Username Error: Please enter User Name Password Error: Please enter Password Sign in Forgot Password? Forgot Username? Download the Access App: iOS | Android Sign in via OpenAthens Sign in via Shibboleth You already have access! Please proceed to your institution's subscription. Create a free profile for additional features.