Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content + • Painful, nonsuppurative inflammation of costochondral cartilage• Unknown cause• May represent seronegative rheumatic disease• Often self-limited• Unilateral or bilateral• Involves second-fourth costal cartilages +++ Symptoms and Signs + • Local swelling, tenderness in parasternal area +++ Imaging Findings + • Bone scan: Can localize inflamed costochondral junctions• Chest CT: Can localize, but less sensitive than bone scan• Transthoracic echocardiography: May demonstrate pathologic cartilage hyperechogenicity +++ Rule Out + • Costochondral neoplasm: if symptoms last longer than 3 wks• Breast pain/causes + • Physical exam• Consider chest CT or bone scan; usually not needed + • If symptomatic, NSAIDs, local or systemic corticosteroids +++ Surgery +++ Indications + • If symptoms longer than 3 wks and mass is present, consider neoplasm and excise +++ References ++Jensen S. Musculoskeletal causes of chest pain. Australian Family Physician 2001;30:834. [PubMed: 11676310] Your Access profile is currently affiliated with '[InstitutionA]' and is in the process of switching affiliations to '[InstitutionB]'. Please click ‘Continue’ to continue the affiliation switch, otherwise click ‘Cancel’ to cancel signing in. Get Free Access Through Your Institution Learn how to see if your library subscribes to McGraw Hill Medical products. Subscribe: Institutional or Individual Sign In Username Error: Please enter User Name Password Error: Please enter Password Forgot Password? Forgot Username? Sign in via OpenAthens Sign in via Shibboleth