Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content + • Hematemesis or coffee ground emesis following forceful vomiting or retching• Epigastric pain +++ Epidemiology + • Responsible for about 10% of cases of acute upper GI hemorrhage• Lesion consists of a 1- to 4-cm longitudinal tear in the gastric mucosa near the esophagogastric junction, extending through the mucosa and submucosa but not usually into the muscularis mucosae• About 75% of these lesions are confined to the stomach; 20% straddle the esophagogastric junction; and 5% are entirely within the distal esophagus• 67% of patients have a hiatal hernia• In about 90% of patients, the bleeding stops spontaneously• The majority of patients are alcoholics +++ Symptoms and Signs + • The patient first vomits food and gastric contents, followed by forceful retching and then bloody vomitus• Epigastric pain• Epigastric tenderness +++ Laboratory Findings + • HGB may be unchanged because of acute blood loss• Obtain CBC, type and cross, prothrombin time (PT), partial thromboplastin time (PTT), international normalized ratio (INR) +++ Imaging Findings + • Upper GI endoscopy: Evidence of gastric and/or distal esophageal mucosal tear with bleeding + • As in any case of acute upper GI bleeding, endoscopy should be performed emergently for diagnosis and possible treatment +++ Rule Out + • Boerhaave syndrome: rupture of the distal esophagus produced by vomiting• Other causes of upper GI hemorrhage + • Admission to ICU• Laboratory tests (type and cross, CBC, PT, PTT, INR)• NG lavage• Upper GI endoscopy +++ When to Admit + • All cases of acute GI hemorrhage should be admitted + • The bleeding can sometimes be controlled by endoscopic therapy• Surgical repair by gastrotomy and oversewing the tears +++ Surgery +++ Indications + • Persistent or recurrent bleeding after endoscopic treatment +++ Medications + • H2 blockers, proton pump inhibitors to possibly decrease risk of rebleeding +++ Treatment Monitoring + • Serial Hgb to evaluate for ongoing blood loss +++ Complications + • Recurrent or ongoing bleeding after endoscopic treatment +++ Prognosis + • Postoperative recurrence is rare +++ References ++Kortas DY. Mallory-Weiss tear: predisposing factors and predictors of a complicated course. Am J Gastroenterol. 2001;96:2863. [PubMed: 11693318] Your Access profile is currently affiliated with [InstitutionA] and is in the process of switching affiliations to [InstitutionB]. Please select how you would like to proceed. Keep the current affiliation with [InstitutionA] and continue with the Access profile sign in process Switch affiliation to [InstitutionB] and continue with the Access profile sign in process Get Free Access Through Your Institution Learn how to see if your library subscribes to McGraw Hill Medical products. Subscribe: Institutional or Individual Sign In Error: Incorrect UserName or Password Username Error: Please enter User Name Password Error: Please enter Password Sign in Forgot Password? Forgot Username? Sign in via OpenAthens Sign in via Shibboleth You already have access! Please proceed to your institution's subscription. Create a free profile for additional features.