Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content + • Endoscopic or contrast radiographic evidence of diverticulum +++ Epidemiology + • Duodenal pulsion diverticula are acquired outpouchings of the mucosa and submucosa• Found in 20% of autopsies and 5-10% of upper GI series• 90% are on the medial aspect of the duodenum• Most are solitary and within 2.5 cm of the ampulla of Vater• Rare before age 40• Symptoms are uncommon, and only 1% of cases found by x-ray warrant surgery• Wind sock type of congenital intraluminal diverticulum is rare +++ Symptoms and Signs + • Most are asymptomatic• A few patients have chronic postprandial abdominal pain or dyspepsia• May present with symptoms from complications of diverticulum-Hemorrhage-Perforation-Pancreatitis-Biliary obstruction• Wind sock type of intraluminal diverticulum usually presents with vague epigastric pain and postprandial fullness-Intestinal bleeding or pancreatitis is occasionally seen +++ Laboratory Findings + • Anemia +++ Imaging Findings + • Diverticulum visualized on upper GI contrast radiographic studies or upper GI endoscopy + • Suspect duodenal diverticula in patients with upper GI bleeding, perforation or biliary obstruction in which no other source is evident +++ Rule Out + • Other causes of upper GI perforation, bleeding, acute pancreatitis, or biliary obstruction + • Signs and symptoms of duodenal diverticula or complications• The diagnosis can be made by upper GI contrast radiographic studies or upper GI endoscopy +++ When to Admit + • Upper GI bleeding• Perforation• Biliary obstruction• Pancreatitis• Severe abdominal pain + • Excision and a 2-layer closure• Endoscopic sphincterotomy or stent placement may be preferable to treat biliary obstruction +++ Surgery +++ Indications + • All complications• Severe persistent postprandial abdominal pain or dyspepsia +++ Contraindications + • Asymptomatic patients +++ Medications + • Antacids and anticholinergics +++ Complications + • Bleeding• Perforation• Acute pancreatitis• Biliary obstruction +++ Prognosis + • Good with expedient surgical treatment of complications +++ References ++Lobo DN et al. Periampullary diverticula and pancreaticobiliary disease. Br J Surg. 1999;86:588. [PubMed: 10361174] Your MyAccess profile is currently affiliated with '[InstitutionA]' and is in the process of switching affiliations to '[InstitutionB]'. Please click ‘Continue’ to continue the affiliation switch, otherwise click ‘Cancel’ to cancel signing in. Get Free Access Through Your Institution Learn how to see if your library subscribes to McGraw Hill Medical products. Subscribe: Institutional or Individual Sign In Username Error: Please enter User Name Password Error: Please enter Password Forgot Username? Forgot Password? Sign in via OpenAthens Sign in via Shibboleth