Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content +++ Penetrating Injuries + • Local and regional effects are determined by mechanism of vessel injury• Stab wounds, low-velocity (< 2000 ft/s) bullet wounds, iatrogenic injuries, and inadvertent intra-arterial injection of drugs produce less soft-tissue injury and less disruption of collateral circulation• High-velocity missiles produce more extensive vascular injuries, which involve massive destruction and contamination of surrounding tissues• Cavitational effect of high-velocity injury causes additional injury and may produce arterial thrombosis due to disrupted intima even when vessel not directly traumatized• Shotgun blasts produce widespread damage and have higher likelihood of infection +++ Blunt Injuries + • Motor vehicle accidents are a major cause of blunt arterial injuries• Most arterial injuries are indirect due to fractures• Especially likely near joints where vessels are relatively fixed and vulnerable to shear forces• Contusions or crush injuries may result in complete or partial disruption of arteries +++ Epidemiology + • Peripheral vascular trauma typically occurs in young men between the ages of 20 and 40 years• Blunt trauma is the principal cause of over 8000 cases of thoracic aortic injuries per year in United States• About 10-15% of deaths from MVA involve thoracic aortic rupture• Most aortic ruptures occur in patients aged 20-30 years, with a 9:1 male to female predominance• 10-20% of patients with acute thoracic disruption survive the initial trauma-Of these, 30% will die within 6 hours, 40% with 24 hours, 72% in first week, and 90% within 10 weeks without treatment• Aortic disruption generally occurs at aortic isthmus (between left subclavian and ligamentum arteriosum) +++ Symptoms and Signs +++ Hemorrhage + • When pulsatile external hemorrhage is present, diagnosis of arterial injury is obvious• When blood accumulates in deep tissues the only manifestation may be shock• Thrombus may form at ends of severed vessels making diagnosis difficult• Presence of pulses distal to injury DO NOT preclude arterial injury (as many as 20% of injuries will be associated with preserved distal pulses) +++ Ischemia + • Must be diagnosed promptly to prevent tissue loss• Must be suspected when patient has 1 or more of the "5 Ps": pain, pallor, paralysis, paresthesias, pulselessness +++ False Aneurysm + • Wall is primarily composed of fibrous tissue derived from nearby tissue (not arterial tissue)• May rupture at any time• Continue to expand due to absence of elastic fibers• Spontaneous resolution is unlikely if > 3 cm• Symptoms gradually appear with compression of surrounding nerves or collateral vessels from rupture or thrombosis +++ Arteriovenous Fistula (AVF) + • With simultaneous injury of adjacent artery and vein, a fistula may form that allows blood from the artery to enter the vein• Long-standing AVF can lead to ... Your Access profile is currently affiliated with [InstitutionA] and is in the process of switching affiliations to [InstitutionB]. Please select how you would like to proceed. Keep the current affiliation with [InstitutionA] and continue with the Access profile sign in process Switch affiliation to [InstitutionB] and continue with the Access profile sign in process Get Free Access Through Your Institution Learn how to see if your library subscribes to McGraw Hill Medical products. Subscribe: Institutional or Individual Sign In Error: Incorrect UserName or Password Username Error: Please enter User Name Password Error: Please enter Password Sign in Forgot Password? Forgot Username? Sign in via OpenAthens Sign in via Shibboleth You already have access! Please proceed to your institution's subscription. Create a free profile for additional features.