Sections View Full Chapter Figures Tables Videos Full Chapter Figures Tables Videos Supplementary Content + • Elevated serum pH (> 7.45)• Increased serum HCO3 +++ Epidemiology + • Most common acid-base disturbance in surgical patients• Pathogenesis involves loss of H+ via NG suction, volume depletion, and hypokalemia +++ Laboratory Findings + • Elevated serum pH• Increased serum HCO3• Paradoxical aciduria• Hypokalemia + • May be mixed, most commonly with respiratory acidosis, but ventilatory compensation is limited• Usually marked volume depletion + • Serum electrolytes• ABG measurement• Urine electrolytes• Urine pH + • Fluid resuscitation (usually with normal saline)• Potassium repletion as KCl +++ Treatment Monitoring + • Serial ABG measurement +++ Prognosis + • Excellent +++ Prevention + • Maintain euvolemia• Potassium supplementation +++ References ++Adrogue HJ et al. Management of life-threatening acid-base disorders. (Two parts.) N Engl J Med. 1998;338:26, 107. Your MyAccess profile is currently affiliated with '[InstitutionA]' and is in the process of switching affiliations to '[InstitutionB]'. Please click ‘Continue’ to continue the affiliation switch, otherwise click ‘Cancel’ to cancel signing in. Get Free Access Through Your Institution Learn how to see if your library subscribes to McGraw Hill Medical products. Subscribe: Institutional or Individual Sign In Username Error: Please enter User Name Password Error: Please enter Password Forgot Username? Forgot Password? Sign in via OpenAthens Sign in via Shibboleth