Sections View Full Chapter Figures Tables Videos Annotate Full Chapter Figures Tables Videos Supplementary Content + • Elevated serum pH (> 7.45)• Increased serum HCO3 +++ Epidemiology + • Most common acid-base disturbance in surgical patients• Pathogenesis involves loss of H+ via NG suction, volume depletion, and hypokalemia +++ Laboratory Findings + • Elevated serum pH• Increased serum HCO3• Paradoxical aciduria• Hypokalemia + • May be mixed, most commonly with respiratory acidosis, but ventilatory compensation is limited• Usually marked volume depletion + • Serum electrolytes• ABG measurement• Urine electrolytes• Urine pH + • Fluid resuscitation (usually with normal saline)• Potassium repletion as KCl +++ Treatment Monitoring + • Serial ABG measurement +++ Prognosis + • Excellent +++ Prevention + • Maintain euvolemia• Potassium supplementation +++ References ++Adrogue HJ et al. Management of life-threatening acid-base disorders. (Two parts.) N Engl J Med. 1998;338:26, 107. Your Access profile is currently affiliated with [InstitutionA] and is in the process of switching affiliations to [InstitutionB]. Please select how you would like to proceed. Keep the current affiliation with [InstitutionA] and continue with the Access profile sign in process Switch affiliation to [InstitutionB] and continue with the Access profile sign in process Get Free Access Through Your Institution Learn how to see if your library subscribes to McGraw Hill Medical products. Subscribe: Institutional or Individual Sign In Error: Incorrect UserName or Password Username Error: Please enter User Name Password Error: Please enter Password Sign in Forgot Password? Forgot Username? Download the Access App: iOS | Android Sign in via OpenAthens Sign in via Shibboleth You already have access! Please proceed to your institution's subscription. Create a free profile for additional features.