This will vary, depending upon the requirement for whole blood replacement. Within a short time after splenectomy for a blood dyscrasia involving a bleeding tendency, it is usually noted that the platelet count rises rapidly; thus, transfusion may be unnecessary for this purpose. It is good practice to monitor platelet counts postoperatively, even in elective procedures, because of the marked thrombocytosis that is occasionally seen. In patients with markedly elevated platelet counts or abnormal platelet function, anticoagulants, such as acetylsalicylic acid and dipyridamole, may be indicated. Anticoagulants are rarely necessary in routine splenectomy. A marked leukocytosis commonly follows splenectomy and should not be interpreted as indicative of infection. Constant gastric suction for a day or so is often advisable. The patient is permitted out of bed on the first postoperative day. Fluid balance is carefully maintained according to the patient's general condition. Any steroid therapy given preoperatively is continued during the postoperative period. Further steroid therapy will be regulated by the hematologist, who will be guided by the response of the patient's blood picture to splenectomy. In patients with secondary hypersplenism, their primary disease will not be altered, although the patient's life has been saved or prolonged by removal of the overactive spleen. The incidence of venous thrombosis is increased when the splenectomy is performed for myeloproliferative disorders or lymphomas. Anticoagulant prophylaxis should be considered in such patients. Atelectasis of the left basal lobe is one of the common complications after splenectomy. When complete splenectomy has been performed, patients should be informed and urged to seek immediate medical attention at the first sign or symptom of infection. Daily oral penicillin for an indefinite period has been suggested for patients of all ages. Polyvalent vaccines for pneumococcus, Haemophilus influenzae, and Neisseria meningitidis are also suggested except for pregnant women.