Mobilization of the right colon is shown by a lateral to medial approach. A medial to lateral approach may be used but is not described here. In the lateral medial approach, mobilization begins at the cecum. The patient is placed in the Trendelenburg position and tilted 30 degrees to the left. The cecum is grasped with an atraumatic instrument and retracted medially and anteriorly (Figure 2). Using a monopolar cautery endoscissors or an ultrasonic device, an incision is made in the peritoneal reflection close to the lateral wall of the bowel at the tip of the cecum (Figure 2). The assistant then grasps the ascending colon and retracts it medial and cephalad, permitting the incision to be extended upward to the region of the hepatic flexure using a traction counter-traction technique (Figure 3). As the dissection begins, care should be taken to avoid ureteral injury (Figure 3). As one approaches the hepatic flexure, the duodenum may be visualized and protected (Figure 3). For mobilization of the hepatic flexure, the patient should be placed in the reverse Trendelenburg position. If there is a 10- to 12-mm trocar in the right lower quadrant, repositioning the laparoscope to this sight may provide better visualization. The hepatic flexure is then retracted medially and inferiorly. An ultrasonic device is used to divide the peritoneal attachments (Figure 3). Care is taken to avoid injury to the underlying duodenum during hepatic flexure mobilization. For mobilization of the hepatic flexure the patient should be placed in the reverse Trendelenburg. If there is a 10-12 mm trocar in the right lower quadrant reposition the laparoscope to this site may provide better visualization. The hepatic flexure is then retracted medially and inferiorly. An ultrasonic device is used to divide the peritoneal attachments (Figures 4A and 4B). Next the proximal transverse colon is mobilized by dividing the omental attachments along the line of dissection in Figure 2. The assistant grasps the omentum and holds this upward. The surgeon grasps the mesenteric side of the transverse colon to put tension on the omental attachments. The omental attachments are divided with ultrasonic shears or electrocautery taking care not to injure the colon. Division of the gastro colic ligament is frequently necessary to completely mobilize the hepatic flexure from the liver. The extent of omental detachment may vary depending on the location of the lesion and the degree of reach needed.