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Chapter 30. Fungal Rhinosinusitis
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Which of the following portends a better prognosis in acute invasive fungal sinusitis?
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A. Lack of visual or neurological symptoms
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B. Aspergillus as causative fungus
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C. Aggressive open-approach resection
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D. Diabetic patient in ketoacidosis
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Which of the following is true regarding allergic fungal rhinosinusitis?
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A. Oral antifungals may reduce postoperative mucosal inflammation and recurrence of disease.
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B. Positive fungal cultures are required for diagnosis and directed antifungal therapy.
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C. Surgery is usually not necessary as polyps and mucin respond readily to appropriate medical management.
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D. More than IgE-mediated hypersensitivity, robust T helper 2-driven adaptive immune response to fungal antigen drive the AFS inflammatory cascade.
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Which is the best treatment for invasive sinusitis of hyaline mold with regular septate hyphae branching at acute angles?
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B. Liposomal amphotericin B
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D. IV piperacillin-tazobactam
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How is chronic invasive sinusitis clinically differentiated from acute invasive fungal sinusitis?
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B. Time course of symptoms
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C. Degree of extrasinus invasion
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D. Fungal stain and culture
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Which of the following is false in acute invasive fungal sinusitis?
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A. Oral antifungals have no role in the treatment of invasive fungal sinusitis.
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B. Mucor growth is optimized in acidotic conditions due to an increased availability of serum iron.
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C. Infection with Mucorales spp. is more destructive and fatal than Aspergillus spp.
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D. Invasive disease by P. boydii is resistant to amphotericin B and requires voriconazole.