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Test Taking Tips
The most commonly tested mechanism of actions of drugs are succinylcholine (vs other paralytics), imatinib, fluoroquinolones, warfarin, and corticosteroids. Don't over-memorize intricate details of exotic drug classes.
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What are some basic drug properties?
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What is first-order kinetics?
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What is zero-order kinetics?
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What is the primary role of the P450 system?
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What are some of the inducers of the P450 system?
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Cigarette smoke, phenobarbital, rifampin, ethanol, INH, phenytoin, etc
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What are some of the inhibitors of the P450 system?
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Grapefruit, erythromycin, nelfinavir, itraconazole, etc
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What is half-life of a drug?
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What is a Phase I reaction?
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What is a Phase II reaction?
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Synthetic reaction, for example, conjugation, methylation, sulfation, etc
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What are some treatments for achalasia?
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What is the management for esophageal varices bleeding?
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What are some treatment options for reflux disease?
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Selective H2 blockers (cimetidine, ranitidine, etc) = 24-hour acid reduction by 70%.
Proton pump inhibitors (pantoprazole, omeprazole, etc) = 10% rebound hyperacidity after discontinuing due to hypergastrinemia
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What are the D2 agonists motility agents and how do they work?
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