RT Book, Section
A1 Shah, Prashant C.
A1 McNamee, Ciaran J.
A2 Sugarbaker, David J.
A2 Bueno, Raphael
A2 Colson, Yolonda L.
A2 Jaklitsch, Michael T.
A2 Krasna, Mark J.
A2 Mentzer, Steven J.
A2 Williams, Marcia
A2 Adams, Ann
SR Print(0)
ID 1105847748
T1 Malignant Primary Anterior Mediastinal Tumors
T2 Adult Chest Surgery, 2e
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 978-0-07-178189-3
LK accesssurgery.mhmedical.com/content.aspx?aid=1105847748
RD 2024/04/19
AB Among  the  three  mediastinal  compartments,  the  anterior  compartment  has  the  greatest  potential  for  developing  a  primary  mediastinal  malignancy.  Malignant  tumors  often  are  symptomatic  and  have  considerable  bulk  compared  with  their  benign  counterparts.  The  most  common  primary  malignant  tumors  of  the  anterior  mediastinum  include  invasive  thymomas,  seminomas,  nonseminomatous  germ  cell  tumors  (GCTs),  malignant  teratomas,  and  lymphomas.  Commonly,  at  presentation,  these  masses  manifest  clinical  symptoms  as  a  result  of  either  extrinsic  compression  of  neighboring  mediastinal  structures  or  due  to  paraneoplastic  syndromes.  It  is  important  to  identify  the  specific  pathology  of  these  tumors,  as  each  of  these  clinical  entities  requires  a  unique  treatment  strategy  with  different  clinical  outcome  and  prognosis.