RT Book, Section
A1 Baldini, Elizabeth H.
A2 Sugarbaker, David J.
A2 Bueno, Raphael
A2 Colson, Yolonda L.
A2 Jaklitsch, Michael T.
A2 Krasna, Mark J.
A2 Mentzer, Steven J.
A2 Williams, Marcia
A2 Adams, Ann
SR Print(0)
ID 1105845142
T1 Radiation Therapy for Mesothelioma
T2 Adult Chest Surgery, 2e
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 978-0-07-178189-3
LK accesssurgery.mhmedical.com/content.aspx?aid=1105845142
RD 2024/04/23
AB Treatment  of  malignant  pleural  mesothelioma  with  radiation  therapy  (RT)  is  extremely  challenging.  The  target  volume  for  treatment  is  very  large,  involving  almost  the  entire  hemithorax,  and  within  and  adjacent  to  this  treatment  volume,  there  are  many  normal  structures  with  low  tolerances  to  radiation.  Consequently,  it  is  very  difficult  to  create  treatment  plans  that  deliver  satisfactorily  high  doses  to  the  complex  target  volume  yet  minimal  doses  to  the  adjacent  radiosensitive  normal  organs.  This  chapter  will  review  the  history,  current  approaches,  and  future  ideas  for  the  treatment  of  pleural  mesothelioma  with  radiotherapy  in  definitive,  adjuvant,  and  palliative  settings.