RT Book, Section
A1 Feng, Xin-Hua
A1 Lin, Xia
A1 Yu, Juehua
A1 Nemunaitis, John
A1 Brunicardi, F. Charles
A2 Brunicardi, F. Charles
A2 Andersen, Dana K.
A2 Billiar, Timothy R.
A2 Dunn, David L.
A2 Hunter, John G.
A2 Matthews, Jeffrey B.
A2 Pollock, Raphael E.
SR Print(0)
ID 1117743393
T1 Molecular and Genomic Surgery
T2 Schwartz's Principles of Surgery, 10e
YR 2015
FD 2015
PB McGraw-Hill Education
PP New York, NY
SN 9780071796743
LK accesssurgery.mhmedical.com/content.aspx?aid=1117743393
RD 2024/04/25
AB Biological  sciences  developed  drastically  in  last  60  years  after  the  uncovering  of  DNA  structure  by  Watson  and  CrickThe  completion  of  the  human  genome  sequence  in  2003  represents  a  great  milestone  in  modern  science.The  technology  emerging  from  molecular  and  cellular  biology  has  revolutionized  the  understanding  of  disease  and  will  radically  transform  the  practice  of  surgery.The  use  of  genetically  modified  mouse  models  and  cell  lines  using  gene  therapy  and  RNA  interference  therapy  has  greatly  contributed  to  the  understanding  of  the  molecular  basis  for  human  diseases  and  targeted  therapies.The  sequencing  of  each  individual’s  genome  has  the  potential  to  improve  the  predication,  prevention,  and  targeted  treatment  of  disease,  resulting  in  personalized  medicine  and  surgery.The  use  of  functional  genomics  and  modern  molecular  analyses  will  facilitate  the  discovery  of  actionable  genes  to  guide  choice  of  care.