RT Book, Section
A1 Nelson, Kristen
A1 Vricella, Luca A.
A2 Yuh, David D.
A2 Vricella, Luca A.
A2 Yang, Stephen C.
A2 Doty, John R.
SR Print(0)
ID 1104599463
T1 Ventricular Assist Devices in Children
T2 Johns Hopkins Textbook of Cardiothoracic Surgery
YR 2014
FD 2014
PB McGraw-Hill Education
PP New York, NY
SN 978-0-07-166350-2
LK accesssurgery.mhmedical.com/content.aspx?aid=1104599463
RD 2024/04/25
AB The  parallel  growth  of  pediatric  cardiac  surgery  and  ventricular  assist  device  (VAD)  technology  has  led  to  the  development  of  mechanical  support  specifically  tailored  to  the  management  of  pediatric  heart  failure.  Pediatric  VADs  are  used  for  heart  failure  refractory  to  conventional  medical  therapy  and  act  as  bridges  most  often  to  transplantation,  but  may  also  act  as  a  bridge  to  recovery.  Each  one  of  the  numerous  devices  currently  available  has  specific  advantages,  but  device  selection  must  be  individualized  to  the  patient’s  particular  anatomy  and  clinical  circumstances.  A  large  NIH  trial  is  currently  ongoing  to  further  develop  continuous  flow  VADs  for  the  smaller  pediatric  population,  due  to  the  promising  results  seen  in  adult  continuous  flow  device  studies.  Anticoagulation  and  infection  prophylaxis  remain  major  concerns  in  the  management  of  pediatric  patients  undergoing  VAD  placement,  but  protocolized  management  will  allow  us  to  further  study  the  complex  interactions  between  inflammation,  immunity  and  use  of  VADs  in  the  pediatric  population.