RT Book, Section A1 Doherty, Gerard M. SR Print(0) ID 58113088 T1 Hodgkin Lymphoma T2 Quick Answers Surgery YR 2010 FD 2010 PB The McGraw-Hill Companies PP New York, NY SN LK accesssurgery.mhmedical.com/content.aspx?aid=58113088 RD 2024/04/19 AB • A malignant neoplasm that originates in lymphoid tissue• Characterized histologically by the presence of Reed-Sternberg cells• Develops in lymph nodes and spreads in an orderly fashion to contiguous lymph node beds• Several histologic subtypes exist based on lymphocyte infiltration:-Nodular sclerosis: 70%-Mixed cellularity: 20%-Lymphocyte predominance: 6%-Lymphocyte depletion: 2%• Most important prognostic factor is the disease stage-Ann Arbor staging system most accepted classification