RT Book, Section A1 Clancy, Thomas E. A1 Ashley, Stanley W. A2 Zinner, Michael J. A2 Ashley, Stanley W. SR Print(0) ID 57019196 T1 Chapter 54. Management of Acute Pancreatitis T2 Maingot's Abdominal Operations, 12e YR 2013 FD 2013 PB The McGraw-Hill Companies PP New York, NY SN 978-0-07-163388-8 LK accesssurgery.mhmedical.com/content.aspx?aid=57019196 RD 2024/04/24 AB Acute pancreatitis includes a wide spectrum of disease, from mild self-limiting symptoms to a fulminant process with multiple organ failure and high mortality. Of the approximately 185,000 patients who develop acute pancreatitis each year in the United States, most experience relatively minor episodes of disease characterized by mild parenchymal edema without distant organ dysfunction and an uneventful recovery.1 Severe episodes, however, may involve a progression to extensive pancreatic necrosis, development of the systemic inflammatory response syndrome (SIRS), multiorgan failure, rapid clinical deterioration, and even death.2,3 Although the overall mortality rate with acute pancreatitis is 2–10%, this is primarily related to the 10–30% of patients with severe disease characterized by pancreatic and peripancreatic necrosis.