RT Book, Section
A1 Forbes, Shawn
A1 Messenger, David
A1 McLeod, Robin S.
A2 Zinner, Michael J.
A2 Ashley, Stanley W.
SR Print(0)
ID 57014377
T1 Chapter 34. Ulcerative Colitis
T2 Maingot's Abdominal Operations, 12e
YR 2013
FD 2013
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-163388-8
LK accesssurgery.mhmedical.com/content.aspx?aid=57014377
RD 2024/04/19
AB Ulcerative  colitis,  one  of  the  idiopathic  inflammatory  bowel  diseases  (IBDs),  is  a  chronic  disease  that  affects  the  mucosa  of  the  rectum  and  colon.  Although  Hippocrates  described  diarrheal  diseases  that  were  colitis-like  well  before  360  bc,  it  was  not  until  the  late  1800s  that  ulcerative  colitis  was  distinguished  clinically  from  common  infectious  enteritis.  Sir  Samuel  Wilks  of  London  is  credited  with  the  first  medical  account  of  colitis.  In  1859,  he  described  a  42-year-old  woman  who  died  after  several  months  of  diarrhea  and  fever.  Postmortem  examination  revealed  a  transmural  ulcerative  inflammation  of  the  colon  and  terminal  ileum  that,  while  originally  designated  as  “simple  ulcerative  colitis,”  may  in  fact  have  been  Crohn's  disease.  A  subsequent  case  report  in  1875,  again  by  Wilks  and  Walter  Moxon,  described  ulceration  and  inflammation  of  the  entire  colon  in  a  young  woman  who  had  succumbed  to  severe  bloody  diarrhea,  and  it  is  more  likely  the  first  detailed  account  of  ulcerative  colitis.