RT Book, Section
A1 Lee, Brian K.
A1 Vincenti, Flavio G.
A2 McAninch, Jack W.
A2 Lue, Tom F.
SR Print(0)
ID 56949413
T1 Chapter 35. Chronic Kidney Disease & Renal Replacement Therapy
T2 Smith & Tanagho's General Urology, 18e
YR 2013
FD 2013
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-162497-8
LK accesssurgery.mhmedical.com/content.aspx?aid=56949413
RD 2024/04/20
AB In  chronic  kidney  disease  (CKD),  reduced  clearance  of  certain  solutes  principally  excreted  by  the  kidney  results  in  their  retention  in  the  body  fluids.  The  solutes  are  end  products  of  endogenous  metabolism  as  well  as  exogenous  substances  (eg,  drugs).  The  most  commonly  measured  indicators  of  renal  failure  are  blood  urea  nitrogen  and  serum  creatinine.  The  renal  clearance  of  creatinine  (as  calculated  from  a  24-hour  urine  collection)  is  often  used  as  a  surrogate  measure  of  glomerular  filtration  rate  (GFR).