RT Book, Section
A1 Sheikh, Ahmad Y.
A1 Joyce, David L.
A1 Mallidi, Hari R.
A1 Robbins, Robert C.
A2 Cohn, Lawrence H.
SR Print(0)
ID 55930023
T1 Chapter 65. Lung Transplantation and Heart-Lung Transplantation
T2 Cardiac Surgery in the Adult, 4e
YR 2012
FD 2012
PB The McGraw-Hill Companies
PP New York, NY
SN 978-0-07-163310-9
LK accesssurgery.mhmedical.com/content.aspx?aid=55930023
RD 2024/04/18
AB Human  lung  transplantation,  performed  as  a  single  lung,  double  lung,  or  heart-lung  bloc,  has  emerged  as  a  life-saving  procedure  for  patients  with  end-stage  pulmonary  disease.  With  improvement  of  operative  techniques,  organ  preservation,  and  immunosuppressive  regimens,  combined  heart-lung  and  isolated  lung  transplantation  have  become  common  treatments  for  patients  with  a  variety  of  end-stage  disease  entities.  To  date,  3466  combined  heart-lung  transplants  and  29,732  lung  transplants  have  been  reported  worldwide.1  Although  the  number  of  heart-lung  transplants  performed  annually  has  declined  in  recent  years,  the  number  of  single  lung  transplantation  procedures  remains  stable,  accompanied  by  a  steady  increase  in  bilateral  lung  transplant  procedures  (Fig.  65-1).  Clinical  progress  in  thoracic  organ  transplantation  has  been  considerable,  yet  significant  barriers  that  limit  the  scope  of  these  procedures  still  remain.  These  include  donor  organ  shortage,  limited  preservation  techniques,  graft  rejection,  and  infectious  complications.  This  chapter  summarizes  the  state  of  the  art  in  combined  heart-lung  and  isolated  lung  transplantation.