RT Book, Section
A1 Rosenzweig, Kenneth E.
A2 Sugarbaker, David J.
A2 Bueno, Raphael
A2 Burt, Bryan M.
A2 Groth, Shawn S.
A2 Loor, Gabriel
A2 Wolf, Andrea S.
A2 Williams, Marcia
A2 Adams, Ann
SR Print(0)
ID 1170414144
T1 Radiation Therapy for Mesothelioma
T2 Sugarbaker’s Adult Chest Surgery, 3e
YR 2020
FD 2020
PB McGraw-Hill Education
PP New York, NY
SN 9781260026931
LK accesssurgery.mhmedical.com/content.aspx?aid=1170414144
RD 2024/04/19
AB Treatment  of  malignant  pleural  mesothelioma  with  radiation  therapy  (RT)  is  extremely  challenging.  The  target  volume  for  treatment  is  very  large,  involving  almost  the  entire  hemithorax,  and  within  and  adjacent  to  this  treatment  volume,  there  are  many  normal  structures  with  low  tolerances  to  radiation.  Consequently,  it  is  very  difficult  to  create  treatment  plans  that  deliver  therapeutic  doses  to  the  tumor  target  volume  while  respecting  normal  tissue  tolerances.  This  chapter  reviews  the  history,  current  approaches,  and  future  ideas  for  the  treatment  of  malignant  pleural  mesothelioma  with  radiotherapy  in  definitive,  adjuvant,  and  palliative  settings.