RT Book, Section A1 Zani, Sabino A1 Sosa, Julie Ann A1 Roman, Sanziana A. A2 Morita, Shane Y. A2 Balch, Charles M. A2 Klimberg, V. Suzanne A2 Pawlik, Timothy M. A2 Posner, Mitchell C. A2 Tanabe, Kenneth K. SR Print(0) ID 1145758455 T1 Other Pancreatic Neuroendocrine Tumors T2 Textbook of Complex General Surgical Oncology YR 2018 FD 2018 PB McGraw-Hill Education PP New York, NY SN 9780071793315 LK accesssurgery.mhmedical.com/content.aspx?aid=1145758455 RD 2024/04/19 AB Historically termed “carcinoid” and “islet cell tumors,” pancreatic neuroendocrine tumors (PNETs) comprise a rare group of tumors that range from the spectrum of well-differentiated functional tumors to nonfunctional poorly differentiated carcinomas. This group of tumors often produces hormones resulting in clinically apparent symptoms. Derived from the islet cells of Langerhans, the first islet cell tumor was reported in 1902.1 Since then, 10 different categories of PNETs have been described, with all but one category being associated with a functional syndrome.