TY - CHAP M1 - Book, Section TI - Malignant Primary Anterior Mediastinal Tumors A1 - Shah, Prashant C. A1 - McNamee, Ciaran J. A2 - Sugarbaker, David J. A2 - Bueno, Raphael A2 - Colson, Yolonda L. A2 - Jaklitsch, Michael T. A2 - Krasna, Mark J. A2 - Mentzer, Steven J. A2 - Williams, Marcia A2 - Adams, Ann PY - 2015 T2 - Adult Chest Surgery, 2e AB - Among the three mediastinal compartments, the anterior compartment has the greatest potential for developing a primary mediastinal malignancy. Malignant tumors often are symptomatic and have considerable bulk compared with their benign counterparts. The most common primary malignant tumors of the anterior mediastinum include invasive thymomas, seminomas, nonseminomatous germ cell tumors (GCTs), malignant teratomas, and lymphomas. Commonly, at presentation, these masses manifest clinical symptoms as a result of either extrinsic compression of neighboring mediastinal structures or due to paraneoplastic syndromes. It is important to identify the specific pathology of these tumors, as each of these clinical entities requires a unique treatment strategy with different clinical outcome and prognosis. SN - PB - McGraw-Hill Education CY - New York, NY Y2 - 2024/04/19 UR - accesssurgery.mhmedical.com/content.aspx?aid=1105847748 ER -