TY  - CHAP
M1  - Book, Section
TI  - Chapter 59. Intraductal Therapy
A1  - Goulet Jr., Robert J.
A1  - Tsangaris, Theodore N.
A1  - Love, Susan M.
A2  - Kuerer, Henry M.
PY  - 2010
T2  - Kuerer's Breast Surgical Oncology
AB  - The  epithelium  of  the  breast  ductal  system  is  the  site  of  origin  for  nearly  all  breast  cancers.1,2  The  intraductal  environment  and  the  significance  of  the  secretions  produced  within  the  human  mammary  gland  have  been  debated  for  centuries.  The  recognition  of  the  role  of  carcinogens  in  the  production  of  malignancies  led  to  a  renewed  interest  in  the  ductal  anatomy  and  physiology  in  the  20th  century.  Today,  the  combination  of  technological  enhancement  providing  direct  and  indirect  access  to  the  luminal  milieu  and  advances  in  cellular  methodology  that  hold  the  promise  of  reliable  diagnostic  and  predictive  markers  of  breast  cancer  are  driving  investigators  to  pursue  a  ductal  approach  to  breast  cancer  diagnosis  and  therapy  that  will  be  preemptive  and  accurate  with  less  toxicity  and  breast  disfigurement.  
SN  - 
PB  - The McGraw-Hill Companies
CY  - New York, NY
Y2  - 2024/04/19
UR  - accesssurgery.mhmedical.com/content.aspx?aid=6414173
ER  -