TY - CHAP M1 - Book, Section TI - Tuberculosis, Pulmonary A1 - Doherty, Gerard M. Y1 - 2010 N1 - T2 - Quick Answers Surgery AB - • Gram-positive rods, often dormant but remain alive for the life of the host• Initial infection affects midzone of lungs, causing caseation in a few weeks• Regional hilar lymph nodes become enlarged; most cases arrest at this stage• If progresses, giant cells produce a typical tubercle• Latent disease occurs when dormant tubercles reactivate in elderly or immunocompromised patients• Apical segments of upper lobes most often affected in latent disease• Extrapulmonary disease may involve pericardium, bones, joints, urinary tract, meninges, lymph nodes, pleural space SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/19 UR - accesssurgery.mhmedical.com/content.aspx?aid=58103919 ER -