TY - CHAP M1 - Book, Section TI - Transposition of the Great Arteries A1 - Doherty, Gerard M. Y1 - 2010 N1 - T2 - Quick Answers Surgery AB - • A congenital heart lesion that decreases pulmonary arterial blood flow• Cyanosis and decreased oxygen delivery causes compensatory polycythemia (Hct > 70%) and spontaneous thrombosis• Exercise, acidosis, pain worsens cyanosis, can cause hypoxic spells• β-Blockers (decreases spasm), fluid intake, HCO3 administration, norepinephrine (increases systemic resistance) may help decrease hypoxia• Bronchial and mediastinal arteries enlarge• Ductus arteriosus maintains flow to lungs during fetal development• Early administration of alprostadil can allow time for optimization before definitive treatment SN - PB - The McGraw-Hill Companies CY - New York, NY Y2 - 2024/04/25 UR - accesssurgery.mhmedical.com/content.aspx?aid=58103563 ER -