TY - CHAP M1 - Book, Section TI - Wounds, Bites, and Stings A1 - Cross, Alisa A1 - Celii, Amanda A1 - Albrecht, Roxie M. A2 - Feliciano, David V. A2 - Mattox, Kenneth L. A2 - Moore, Ernest E. Y1 - 2020 N1 - T2 - Trauma, 9e AB - KEY POINTSThe four phases of wound healing are hemostasis, inflammation, proliferation, and maturation/remodeling.Significant influences on wound healing include age, nutrition, body habitus, and social history.The decision to use antibiotics for a wound will depend on host factors (eg, age, comorbidities, immunocompromised state), wound characteristics, and location.Wounds with significant contamination, ischemia, or tissue loss are left open to heal by secondary intention.Transmission of HIV or hepatitis C through saliva from a bite is rare, and HIV testing after human bites is not necessary.Jaws of larger dogs are capable of generating 200 to 450 pounds per square inch of pressure, and fractures under the injury to soft tissue should be ruled out.Rabies is a vaccine-preventable viral disease primarily caused by the bite of a rabid animal and has a worldwide distribution.In up to 40% of patients, the bite of a brown recluse spider will lead to necrosis of soft tissue due to local ischemia.Pit vipers including rattlesnake, water moccasin, and copperhead snakes have a heat-sensing pit located behind their nostrils.Although the mouth of a snake is colonized with bacteria like all animals, local infection following a snakebite is rare. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/04/19 UR - accesssurgery.mhmedical.com/content.aspx?aid=1175135472 ER -