TY  - CHAP
M1  - Book, Section
TI  - Nonoperative Treatment of Malignant Pleural Effusions
A1  - Paul, Subroto
A1  - Zellos, Lambros
A2  - Sugarbaker, David J.
A2  - Bueno, Raphael
A2  - Colson, Yolonda L.
A2  - Jaklitsch, Michael T.
A2  - Krasna, Mark J.
A2  - Mentzer, Steven J.
A2  - Williams, Marcia
A2  - Adams, Ann
PY  - 2015
T2  - Adult Chest Surgery, 2e
AB  - Malignant  pleural  effusions  (MPEs)  cause  considerable  morbidity  for  patients  afflicted  with  cancer.  Metastatic  breast,  lung,  and  ovarian  cancers  account  for  the  majority  of  cases.  An  estimated  150,000  new  patients  are  diagnosed  annually  with  dyspnea  secondary  to  MPE.1,2  Initial  malignant  diagnosis  can  be  established  in  50%  to  60%  of  patients  by  means  of  a  therapeutic  thoracentesis.1,2  However,  the  malignant  effusions  often  recur,  and  patients  require  long-term  palliation.  The  ideal  therapy  permits  expedient,  low-cost  management  of  the  pleural  effusion  with  minimal  morbidity  because  many  of  these  patients  have  terminal  disease.  Operative  management  includes  drainage  through  the  use  of  video-assisted  thoracic  surgery  (VATS)  techniques  combined  with  sclerosis,  as  well  as  operative  placement  of  indwelling  drainage  catheters.2–4  The  operative  techniques  are  described  in  Chapter  120.  Nonoperative  management  of  MPEs,  the  focus  of  this  chapter,  includes  systemic  chemotherapy  and  several  methods  of  mechanical  drainage,  which  may  be  combined  with  pleural  sclerosing  agents.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accesssurgery.mhmedical.com/content.aspx?aid=1105845190
ER  -