TY - CHAP M1 - Book, Section TI - Gastrointestinal Failure A1 - Diaz, Jose J. A1 - Collier, Bryan A2 - Feliciano, David V. A2 - Mattox, Kenneth L. A2 - Moore, Ernest E. PY - 2020 T2 - Trauma, 9e AB - KEY POINTSIn the critically ill or injured patient, gut dysfunction commonly occurs and can take various forms, from food intolerance to life-threating conditions that can progress to multiple organ dysfunction syndrome (MODS) or persistent inflammatory, immunosuppressed, catabolic syndrome (PICS).Gut injury can be described as an ischemia/reperfusion event that can present as severe as nonocclusive small bowel ischemia to the abdominal compartment syndrome.More commonly, gastrointestinal (GI) dysfunction will manifest as gastroesophageal reflux, gastroparesis, duodenogastric ileus, or malabsorption as a manifestation of food intolerance.Recognition of the human microbiome as an important component of gut health and the alterations in the microbiome during critical illness has spurred renewed interest in the microbiology of the GI tract.The chapter will review the pathophysiology and the current best practice recommendations for medical management. SN - PB - McGraw Hill CY - New York, NY Y2 - 2024/04/19 UR - accesssurgery.mhmedical.com/content.aspx?aid=1175136868 ER -