TY  - CHAP
M1  - Book, Section
TI  - Papillary Thyroid Carcinoma
A1  - Finnerty, Brendan M.
A1  - Zarnegar, Rasa
A1  - Fahey , Thomas J.
A2  - Morita, Shane Y.
A2  - Balch, Charles M.
A2  - Klimberg, V. Suzanne
A2  - Pawlik, Timothy M.
A2  - Posner, Mitchell C.
A2  - Tanabe, Kenneth K.
PY  - 2018
T2  - Textbook of Complex General Surgical Oncology
AB  - It  was  not  until  the  19th  century  that  Billroth,  Kocher,  Halsted,  and  others  refined  the  thyroidectomy  operation  into  a  standard  treatment  for  thyroid  cancer  with  advancements  in  anti-septic  technique,  anesthesia,  recurrent  laryngeal  nerve  protection,  and  parathyroid  preservation.1,2  In  the  first  half  of  the  20th  century,  oncologic  resection  for  papillary  thyroid  cancer  (PTC)  commonly  incorporated  a  “block  dissection,”  which  sacrificed  the  sternocleidomastoid  muscle,  spinal  accessory  nerve,  and  marginal  mandibular  branch  of  the  facial  nerve  resulting  in  significant  deformity.  George  Crile  Jr.  heralded  a  more  limited  dissection  with  successful  oncologic  outcomes,  which  sparked  the  on-going  debates  regarding  extent  of  dissection,  implications  of  neck  metastases,  and  prognostic  factors  for  risk  stratification.3  As  early  detection  of  PTC  increased  by  the  1980s  with  the  widespread  use  of  diagnostic  ultrasound  and  fine  needle  aspiration  biopsy,  controversy  regarding  the  management  of  smaller  tumors  grew.  Furthermore,  with  the  development  of  radioactive  iodine  as  a  successful  adjuvant  therapy,  there  has  been  considerable  debate  regarding  specific  indications  for  administration.4,5  Nevertheless,  with  these  advancements,  thyroid  cancer  has  become  a  treatable  disease  and  the  stage  has  been  set  for  development  of  modern-era  treatments,  particularly  molecular-based  targeted  therapeutics.  
SN  - 
PB  - McGraw-Hill Education
CY  - New York, NY
Y2  - 2024/04/19
UR  - accesssurgery.mhmedical.com/content.aspx?aid=1145757416
ER  -