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  • • Elevated serum phosphorus

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Epidemiology

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  • • Renal insufficiency

    • Post-trauma

    • Marked tissue catabolism

    • Excess intake (rarely)

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Symptoms and Signs

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  • • Usually asymptomatic

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Laboratory Findings

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  • • Elevated serum phosphorus

    • Decreased serum calcium

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  • • In perioperative or post-trauma setting, almost always associated with renal insufficiency, even when other factors also present

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  • • Serum electrolytes

    • ABG measurements

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  • • Diuresis

    • Phosphate binding antacids

    • Dialysis

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Medications

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  • • Diuretics

    • Phosphate binding antacids (aluminum hydroxide)

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Treatment Monitoring

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  • • Serum electrolytes

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Prognosis

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  • • Excellent

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References

Klahr S et al. Acute renal failure. N Engl J Med. 1998;338:671.  [PubMed: 9486997]
Frazao JM. Adragao T. Treatment of hyperphosphatemia with sevelamer hydrochloride in dialysis patients: effects on vascular calcification, bone and a close look into the survival data. Kidney International - Supplement. 2008, (111):S38-43.

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