Under ideal circumstances, stereotactic breast biopsy is considered a team endeavor, with essential functions performed by the surgeon, the radiologist, the pathologist, the x-ray technologist, and the histologic technologist. The first step in preparation for a stereotactic core needle breast biopsy is selecting the approach to the breast for the needle insertion (ie, lateral, medial, cranial, or caudal). The shortest approach is usually preferable, as the biopsy probe passes through the smallest volume of breast tissue. In some cases, if the patient intends to wear bikinis or clothing with very low necklines, the physician may choose the caudal or lateral approach in preference to the shortest approach, so that the small incision needed to pass the biopsy device into the breast tissue and resulting scar will not be on an exposed area of the breast. If the surgeon plans to biopsy multiple lesions in the same breast at the same sitting, it may be preferable to choose an approach that allows optimal access to all of the lesions with minimal repositioning of the patient rather than choosing a different approach for each of the multiple lesions and repositioning the patient for each lesion. One should keep in mind that to biopsy different lesions in the same breast from both the lateral and the medial approaches requires taking the patient off the table in between biopsies to reverse the positions of the patient's head and feet.