• Lipomas are slow growing, benign adipose tumors, most often found in the subcutaneous tissues
• Lipomas also occur in the deeper tissues such as the intramuscular septa, thoracic cavity, abdominal organs, and the GI tract
• Histologically, lipomas are composed of mature adipocytes arranged in lobules, surrounded by a fibrous capsule
• Infiltrating lipomas are non-encapsulated benign lesions with extensions into muscle
• Variants of lipomas include angiolipoma, pleomorphic lipoma, spindle cell lipoma, and adenolipoma
• Lipomas are identified in all age groups but most commonly appear first between the ages of 40 and 60
• Multiple lipomas (lipomatosis) associated with hereditary syndromes:
• Hereditary multiple lipomatosis
• Nontender, oval, mobile subcutaneous masses
• Characteristic soft, doughy texture
• Overlying skin normal
• Deeply positioned lipomas typically present as nontender, nonmobile, soft-tissue masses
–Demonstrates the extent of the lesion
–May be able to differentiate between lipoma and liposarcoma
–Useful for deep lesions and/or when malignancy is suspected
• Thorough history and physical exam
• When malignancy is suspected, a MRI may be indicated, especially for large or deep-seated lesions
• Surgical infection
Shelly MJ. MacMahon PJ. Eustace S Radiology of soft tissue tumors including melanoma. Cancer Treatment & Research.
Dalal KM. Antonescu CR. Singer S. Diagnosis and management of lipomatous tumors. Journal of Surgical Oncology.
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